Moving Along newsletter
December 2025 Vol. 29, Issue 4
MDS's quarterly newsletter, providing up-to-date information on new developments in the field of Movement Disorders, as well as MDS announcements and other news.
Top story
Meet the new President of MDS: Prof. David Burn
Get to know Prof. Burn's history in the field and Society, as well as his plans for MDS.
Scientific Updates
What’s next for AMT-130?
A detailed discussion about the promising Huntington’s disease trial results, its many challenges, and how what happens next could affect the regulatory landscape for all neurodegenerative diseases.
A holistic wellness prescription for Parkinson’s disease: New MDS Task Force publication
“I actually think this framework can free us a bit. It reminds us that we, the doctors, are not the be-all and end-all.”
Artificial intelligence and patient care: The secret lies in caring for the patient
Authors share how AI can help place the patient at the center of their care in “the machine will see you now” paper.
MDS Congress Highlights
Highlights from the 2025 MDS International Congress in Honolulu
Discover the important scientific concepts at the center of this year's event.
MDCP Research Article of the Year Award Predicting post-mortem α-synuclein pathology by the combined presence of probable REM sleep behavior disorder and hyposmia
Authors share data on a simple and cost-effective predictive biomarker test for Lewy pathology.
MDJ Review Article of the Year Award Exploration of neurodegenerative diseases using long-read sequencing and optical genome mapping technologies
A broad perspective on the achievements, limitations, challenges, and opportunities for the future.
MDCP Review Article of the Year Award The looming threat of Subacute Sclerosing Panencephalitis: A call for action
Authors highlight dangers and motor manifestations to watch for during global resurgence of measles.
2025 C. David Marsden Presidential Lecture Award Awardee shares his awe for the brain, career highlights, and the value of hope and mentorship
“The best thing you can do as a mentor is to encourage people to question everything.” — A. Jon Stoessl
2025 Stanley Fahn Presidential Lecture Award Better managing the experience of chronic illness
“There’s a difference in the way we talk about ‘having’ diseases, versus ‘being’ sick. There is an additional component. That’s an important thing.” —Mark Edwards
2025 Junior Award Atrophy in Multiple System Atrophy Relates to Mitochondrial and Oligodendrocytic Processes
Study links structural changes to underlying molecular pathways by integrating MRI data with transcriptomic information from the Allen Human Brain Atlas.
2025 Junior Award Cell-type specific bidirectional modulation of STN neurons rescue parkinsonian motor symptom
Awardee discusses inspiration for insights he hopes could eventually guide next-generation DBS.
Honorary Membership Award Awardee details MDS's impact on his career, the field
“MDS has witnessed my career in movement disorders; more than a passive observer, it has been a real catalyst” — Marcello Merello
Honorary Membership Award The honor of being elected an Honorary Member of MDS
“The fight against movement disorders is a shared responsibility that spans disciplines, continents, and cultures.” — Glenn T. Stebbins
The “new essential” for Parkinson’s management
Insights from the "Comprehensive Care in Parkinsonism: Beyond Medication" plenary session.
Features
How (and why) to get started in neurophysiology
“If you love phenotyping, really observing and understanding movement, then neurophysiology will enrich your clinical life.”
MDS Podcast: Where the community shapes the conversation
Editorial board grows to cover a variety of topics with broad expertise, adds interesting special series.
In Memoriam:
Dr. Mark Hallett
(1943-2025)
In Memoriam:
Dr. Martje van Egmond
(1980–2025)
YMG paper highlights
Benign idiopathic myoclonus: A new clinical entity
This new observation may shed light on a newly defined subtype of myoclonus requiring specific and limited diagnostic and therapeutical management.
Interpretable machine learning for cross-cohort prediction of motor fluctuations in Parkinson's disease
Study provides a quantitative and generalizable framework that might also serve as a template for the study of other disease outcomes and conditions.
Towards adaptive deep brain stimulation for non-motor symptoms in Parkinson's disease?
Advancing non-motor aDBS may require a significant shift away from dorsolateral motor STN and beta-based motor biomarkers.
Event Highlights
Women's SIG event celebrates Susan Fox, MDS President-Elect
More than 100 networking attendees engage in themed networking scavenger hunt and celebration of women in the field.
Bridging a whole continent through collaboration
Highlights from the 3rd LARGE-PD Annual Meeting in Querétaro.
International faculty share insights at the XV Symposium on Movement Disorders of the Colombian Neurology Society (ACN)
Seven thematic modules provided a comprehensive update on recent developments in the field.
Course bridges basic science, clinical neurology, translational imaging
Professionals convene to explore cutting-edge research at the intersection of neuroimaging, molecular pathology, and clinical neuroscience in Parkinson’s disease (PD).
Highlights from movement disorders sessions at the World Congress of Neurology
Topics included toxins, non-motor symptoms, rare disorders, and more.
Highlights of the 4th Egyptian Movement Disorders Conference & School: Advancing continuous education
Successful event includes esteemed international experts, new and impactful sessions.
MDS offers first Neuromodulation School in Spanish
Attendees explored emerging technologies and learned via real clinical case presentations.
Highlights from the 1st MDS-endorsed DWEP Course in Istanbul
Focused on tremor, chorea, and myoclonus from phenomenology to treatment.
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Editorial Board
Katarzyna Smilowska, MD, PhD
Moving Along Editor (2023-2025)
Dr. Katarzyna Smilowska is a neurologist specializing in Movement Disorders at the 5th Regional Hospital in Sosnowiec, Poland. She has trained and conducted research at Radboud University Medical Center, Queen Square, and Christian-Albrechts University. She is actively engaged in international collaborations, serving on committees and task forces within MDS, as well as on committees and panels of the European Academy of Neurology.
Catalina Cerquera-Cleves, MD, MSc
Daniel G. Di Luca, MD
Shaimaa El-Jaafary, MD
Sergio Rodriguez-Quiroga, MD
Indu Subramanian, MD
Daniel Gams Massi, MD
Vikram Holla, MD, DM
Elie Matar, BSc(Adv), MD, PhD, FRACP
Vanessa Carvalho, MD